Diabetes in America is the National Institute of Diabetes and Digestive and Kidney Diseases’ compilation and assessment of epidemiologic, public health, clinical research, and clinical trial data focused on diabetes, its complications and treatment, health care utilization, and diabetes prevention in the United States. These data are intended to be a valuable resource for the research community, clinicians, policy makers, and individuals with diabetes, as well as their caregivers and family members. There have been three previous Diabetes in America editions published in 1984, 1995 and 2018. Diabetes in America has been migrated to an exclusively digital format. Starting in 2023, each updated or new article will be available on the National Library of Medicine’s NCBI Bookshelf. Diabetes in America is organized into four broad topic areas --Section I: Spectrum of Diabetes; Section II: Complications of Diabetes and Related Conditions; Section III: Medical Care for Diabetes; and Section IV: Prevention of Diabetes.