Hot-Pressing Metal Covalent Organic Frameworks as Personal Protection Films

Adv Mater. 2024 Mar;36(13):e2311519. doi: 10.1002/adma.202311519. Epub 2023 Dec 27.

Abstract

Effective personal protection is crucial for controlling infectious disease spread. However, commonly used personal protective materials such as disposable masks lack antibacterial/antiviral function and may lead to cross infection. Herein, a polyethylene glycol-assisted solvent-free strategy is proposed to rapidly synthesize a series of the donor-acceptor metal-covalent organic frameworks (MCOFs) (i.e., GZHMU-2, JNM-1, and JNM-2) under air atmosphere and henceforth extend it via in situ hot-pressing process to prepare MCOFs based films with photocatalytic disinfect ability. Best of them, the newly designed GZHMU-2 has a wide absorption spectrum (200 to 1500 nm) and can efficiently produce reactive oxygen species under sunlight irradiation, achieving excellent photocatalytic disinfection performance. After in situ hot-pressing as a film material, the obtained GZHMU-2/NMF can effectively kill E. coli (99.99%), S. aureus (99%), and H1N1 (92.5%), meanwhile possessing good reusability. Noteworthy, the long-term use of a GZHMU-2/NWF-based mask has verified no damage to the living body by measuring the expression of mouse blood routine, lung tissue, and inflammatory factors at the in-vivo level.

Keywords: antibiosis; antiviral; hot‐pressing; metal covalent organic frameworks; photocatalysis.

MeSH terms

  • Animals
  • Anti-Bacterial Agents / pharmacology
  • Escherichia coli
  • Influenza A Virus, H1N1 Subtype*
  • Metal-Organic Frameworks*
  • Mice
  • Staphylococcus aureus

Substances

  • Metal-Organic Frameworks
  • Anti-Bacterial Agents