Lung relapse pattern in children with metastatic Wilms tumor

Pediatr Blood Cancer. 2024 Apr;71(4):e30856. doi: 10.1002/pbc.30856. Epub 2024 Jan 11.

Abstract

Wilms tumor is the most common pediatric renal cancer, and lungs represent the major site of metastasis and recurrence. Relapse occurs in 15%, months or years after treatment; so due to the small sample, acquiring more data about the pattern of lung relapse remains a challenge. The aim of our study was to evaluate if pulmonary relapse, detected by computed tomography (CT), occurred at the initial site of lung metastases or in a different location. According to our data, the CT pattern of lung relapse showed high probability of recurrence at the same site of initial metastasis.

Keywords: Wilms tumor; pediatric oncology; radiology.

MeSH terms

  • Child
  • Humans
  • Kidney Neoplasms* / pathology
  • Lung / pathology
  • Lung Neoplasms* / secondary
  • Neoplasm Recurrence, Local
  • Wilms Tumor* / pathology