Attitudes towards COVID-19 Vaccination in Adults with Haematological Malignancies

Acta Haematol. 2024;147(5):543-554. doi: 10.1159/000536548. Epub 2024 Feb 16.

Abstract

Introduction: Despite people with haematological malignancies being particularly vulnerable to severe COVID-19 infection and complications, vaccine hesitancy may be a barrier to optimal vaccination. This study explored attitudes towards COVID-19 vaccination in people with haematological malignancies.

Methods: People with haematological malignancies at nine Australian health services were surveyed between June and October 2021. Sociodemographic and clinical characteristics were collected. Attitudes towards COVID-19 vaccination were explored using the Oxford COVID-19 Vaccine Hesitancy Scale, the Oxford COVID-19 Vaccine Confidence and Complacency Scale, and the Disease Influenced Vaccine Acceptance Scale-Six. Open-ended comments were qualitatively analysed.

Results: A total of 869 people with haematological malignancies (mean age 64.2 years, 43.6% female) participated. Most participants (85.3%) reported that they had received at least one COVID-19 vaccine dose. Participants who were younger, spoke English as a non-dominant language, and had a shorter time since diagnosis were less likely to be vaccinated. Those who were female or spoke English as their non-dominant language reported greater vaccine side-effect concerns. Younger participants reported greater concerns about the vaccine impacting their treatment.

Conclusion: People with haematological malignancies reported high vaccine uptake; however, targeted education for specific participant groups may address vaccine hesitancy concerns, given the need for COVID-19 vaccine boosters.

Keywords: COVID-19; COVID-19 vaccines; Hematological malignancies; Vaccination.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Australia
  • COVID-19 Vaccines* / administration & dosage
  • COVID-19 Vaccines* / adverse effects
  • COVID-19* / epidemiology
  • COVID-19* / prevention & control
  • COVID-19* / psychology
  • Female
  • Health Knowledge, Attitudes, Practice
  • Hematologic Neoplasms* / psychology
  • Hematologic Neoplasms* / therapy
  • Humans
  • Male
  • Middle Aged
  • Patient Acceptance of Health Care
  • Surveys and Questionnaires
  • Vaccination Hesitancy* / psychology

Substances

  • COVID-19 Vaccines

Grants and funding

This study was not funded from any external source.