Delayed Presentation of Pityriasis Rubra Pilaris in a Patient on Treatment With Ponatinib

Cureus. 2024 Jan 12;16(1):e52155. doi: 10.7759/cureus.52155. eCollection 2024 Jan.

Abstract

Pityriasis rubra pilaris (PRP) is a rare dermatologic condition whose etiology is largely unknown. However, some medications, including ponatinib, have been implicated. Our case features an 80-year-old patient who developed PRP after two-and-a-half years of ponatinib use. We present this case due to the rare presentation of ponatinib-induced PRP as well as its significantly delayed presentation.

Keywords: adverse drug reactions; chronic myeloid leukemia; delayed presentation; pityriasis rubra pilaris; ponatinib.

Publication types

  • Case Reports