Executive summary of the KDIGO 2024 Clinical Practice Guideline for the Management of ANCA-Associated Vasculitis

Kidney Int. 2024 Mar;105(3):447-449. doi: 10.1016/j.kint.2023.10.009.

Abstract

In 2021, the Kidney Disease: Improving Global Outcomes (KDIGO) Guideline for the Management of Glomerular Diseases was published. KDIGO is committed to providing the nephrology community with periodic updates, based on new developments for each disease. For patients with anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV), avacopan received regulatory approval in late 2021, leading to this KDIGO guideline update. In addition, the evidence supporting a lower-dose glucocorticoid induction regimen or even complete replacement of glucocorticoids has become stronger. Herein, an executive summary of the most important guideline changes from the AAV chapter is provided as a quick reference.

Keywords: ANCA-associated vasculitis; KDIGO; glomerular diseases; glomerulonephritis; guideline; systematic review.

Publication types

  • Practice Guideline

MeSH terms

  • Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis* / diagnosis
  • Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis* / drug therapy
  • Antibodies, Antineutrophil Cytoplasmic
  • Glomerulonephritis* / diagnosis
  • Glomerulonephritis* / drug therapy
  • Glucocorticoids / therapeutic use
  • Humans
  • Kidney
  • Nephrology*

Substances

  • Antibodies, Antineutrophil Cytoplasmic
  • Glucocorticoids