An elusive prostate tumour: Metastatic microcystic cribriform carcinoma presenting with imaging-histologic discordance

Chun Khai Loh; Juanita Noeline Chui; Kevin Yinkit Zhuo; Ashan Canagasingham; Alexander Guminski; Warick Delprado; Thomas Eade; Matthew Winter

doi:10.1016/j.eucr.2024.102676

An elusive prostate tumour: Metastatic microcystic cribriform carcinoma presenting with imaging-histologic discordance

Urol Case Rep. 2024 Feb 11:53:102676. doi: 10.1016/j.eucr.2024.102676. eCollection 2024 Mar.

Authors

Chun Khai Loh^{1

2

3}, Juanita Noeline Chui^{2

3}, Kevin Yinkit Zhuo^{1

2}, Ashan Canagasingham^{1

2}, Alexander Guminski^{3

4}, Warick Delprado⁵, Thomas Eade^{3

6}, Matthew Winter^{1

2

3}

Affiliations

¹ Department of Urology, Royal North Shore Hospital, Sydney, NSW, Australia.
² North Shore Urology Research Group, Sydney, NSW, Australia.
³ University of Sydney, Sydney, NSW, Australia.
⁴ Department of Medical Oncology, Royal North Shore Hospital, Sydney, NSW, Australia.
⁵ Douglas Hanly Moir Pathology (Sonic Healthcare), Macquarie Park, NSW, Australia.
⁶ Department of Radiation Oncology, Royal North Shore Hospital, Sydney, NSW, Australia.

Abstract

Microcystic adenocarcinoma is an uncommon histologic variant of prostate carcinoma. Despite its rarity, it has gained increasing recognition over the past decade for its diagnostic challenges and unclear prognostic significance. Herein, we describe a rare case of metastatic microcystic prostate adenocarcinoma, presenting with discordance between imaging and histologic findings. This report highlights the diagnostic and therapeutic challenges of this pathological entity and the importance of multidisciplinary collaboration in the management of intermediate-risk prostate cancer.

Publication types

Case Reports