TICI: a taxon-independent community index for eDNA-based ecological health assessment

PeerJ. 2024 Feb 26:12:e16963. doi: 10.7717/peerj.16963. eCollection 2024.

Abstract

Global biodiversity is declining at an ever-increasing rate. Yet effective policies to mitigate or reverse these declines require ecosystem condition data that are rarely available. Morphology-based bioassessment methods are difficult to scale, limited in scope, suffer prohibitive costs, require skilled taxonomists, and can be applied inconsistently between practitioners. Environmental DNA (eDNA) metabarcoding offers a powerful, reproducible and scalable solution that can survey across the tree-of-life with relatively low cost and minimal expertise for sample collection. However, there remains a need to condense the complex, multidimensional community information into simple, interpretable metrics of ecological health for environmental management purposes. We developed a riverine taxon-independent community index (TICI) that objectively assigns indicator values to amplicon sequence variants (ASVs), and significantly improves the statistical power and utility of eDNA-based bioassessments. The TICI model training step uses the Chessman iterative learning algorithm to assign health indicator scores to a large number of ASVs that are commonly encountered across a wide geographic range. New sites can then be evaluated for ecological health by averaging the indicator value of the ASVs present at the site. We trained a TICI model on an eDNA dataset from 53 well-studied riverine monitoring sites across New Zealand, each sampled with a high level of biological replication (n = 16). Eight short-amplicon metabarcoding assays were used to generate data from a broad taxonomic range, including bacteria, microeukaryotes, fungi, plants, and animals. Site-specific TICI scores were strongly correlated with historical stream condition scores from macroinvertebrate assessments (macroinvertebrate community index or MCI; R2 = 0.82), and TICI variation between sample replicates was minimal (CV = 0.013). Taken together, this demonstrates the potential for taxon-independent eDNA analysis to provide a reliable, robust and low-cost assessment of ecological health that is accessible to environmental managers, decision makers, and the wider community.

Keywords: Biodiversity; Biotic index; Ecological health; Ecology; Taxon-independent analysis; eDNA.

MeSH terms

  • Animals
  • Biodiversity
  • DNA Barcoding, Taxonomic / methods
  • DNA, Environmental* / genetics
  • Ecosystem*
  • Rivers

Substances

  • DNA, Environmental

Grants and funding

This work was supported by a Callaghan Innovation Career Grant, awarded to Wilderlab NZ Ltd. for Amy A Gault (Grant no. WNZAI2002). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.