Improving the diagnosis of AATD with aid of serum protein electrophoresis: a prospective, multicentre, validation study

Clin Chem Lab Med. 2024 Mar 5;62(8):185-188. doi: 10.1515/cclm-2024-0176. Print 2024 Jul 26.

Simone Scarlata^{1

2}, Stefania Ottaviani³, Alfredo Villa⁴, Stefano Baglioni⁵, Filomena Basile⁶, Anna Annunziata⁷, Simona Santangelo^{1

2}, Maria Francesconi^{8

9}, Francesco Arcoleo¹⁰, Alice M Balderacchi³, Silvia Angeletti^{8

9}, Sara Magni³, Angelo G Corsico^{3

11}, Ilaria Ferrarotti^{3

11}

¹ Department of Medicine and Surgery, Research Unit of Geriatrics, 9317 Università Campus Bio-Medico di Roma , Rome, Italy.
² Fondazione Policlinico Universitario Campus Bio-Medico, Operative Research Unit of Internal Medicine, Rome, Italy.
³ Center for Diagnosis of Inherited α1-Antitrypsin Deficiency, Pneumology Unit, 18631 Fondazione IRCCS Policlinico San Matteo , Pavia, Italy.
⁴ Department of Clinical Pathology, Santa Maria della Misericordia Hospital, Perugia, Italy.
⁵ Pulmonary and Respiratory Intensive Care Unit, Santa Maria della Misericordia Hospital, Perugia, Italy.
⁶ 92712 UOC Biochimica Clinica, Azienda ospedaliera dei Colli, Monaldi Hospital , Naples, Italy.
⁷ Unit of Pathophysiology and Respiratory Rehabilitation, Intensive Care Department, 92712 Monaldi Hospital , Naples, Italy.
⁸ Unit of Clinical Laboratory Science, 9317 University Campus Bio-Medico of Rome , Rome, Italy.
⁹ Unit of Laboratory, 18631 Fondazione Policlinico Universitario Campus Bio-Medico , Rome, Italy.
¹⁰ 9341 UOC di Patologia Clinica e Immunologia, AOR Villa Sofia Cervello , Palermo, Italy.
¹¹ Department of Internal Medicine and Therapeutics, Pneumology Unit, 154943 Università di Pavia , Pavia, Italy.

No abstract available

Keywords: alpha-1 antitrypsin deficiency; alpha1-globulin; screening; serum proteins.

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