Inhibition of miR-21: cardioprotective effects in human failing myocardium ex vivo
Eur Heart J
.
2024 Jun 7;45(22):2016-2018.
doi: 10.1093/eurheartj/ehae102.
Authors
Naisam Abbas
1
2
,
Jonas A Haas
1
,
Ke Xiao
2
,
Maximilian Fuchs
2
,
Annette Just
1
,
Andreas Pich
3
,
Filippo Perbellini
1
,
Christopher Werlein
4
,
Fabio Ius
5
,
Arjang Ruhparwar
5
,
Jan Fiedler
2
,
Natalie Weber
1
,
Thomas Thum
1
6
Affiliations
1
Institute of Molecular and Translational Therapeutic Strategies (IMTTS), Hannover Medical School, Carl-Neuberg-Straße 1, 30625 Hannover, Germany.
2
Fraunhofer Institute of Toxicology and Experimental Medicine (ITEM), Hannover, Germany.
3
Institute of Toxicology and Core Unit Proteomics, Hannover Medical School, Hannover, Germany.
4
Institute of Pathology, Hannover Medical School, Hannover, Germany.
5
Department of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, Hannover, Germany.
6
Center for Translational Regenerative Medicine, Hannover Medical School, Carl-Neuberg-Straße 1, 30625 Hannover, Germany.
PMID:
38442291
PMCID:
PMC11156487
DOI:
10.1093/eurheartj/ehae102
No abstract available
MeSH terms
Heart Failure*
Humans
MicroRNAs* / metabolism
Myocardium / metabolism
Myocardium / pathology
Substances
MicroRNAs
MIRN21 microRNA, human
Grants and funding
SFB1470/ERC