Cost-Effectiveness of Radar Localisation Versus Wire Localisation for Wide Local Excision of Non-palpable Breast Cancer

Ann Surg Oncol. 2024 Jun;31(6):3916-3925. doi: 10.1245/s10434-024-15142-x. Epub 2024 Mar 12.

Abstract

Background: Wire localisation (WL) is the "gold standard" localisation technique for wide local excision (WLE) of non-palpable breast lesions but has disadvantages that have led to the development of wireless techniques. This study compared the cost-effectiveness of radar localisation (RL) to WL.

Methods: This was a single-institution study of 110 prospective patients with early-stage breast cancer undergoing WLE using RL with the SCOUT® Surgical Guidance System (2021-2023) compared with a cohort of 110 patients using WL. Margin status, re-excision rates, and surgery delays associated with preoperative localisation were compared. Costs from a third-party payer perspective in Australian dollars (AUD$) calculated by using microcosting, break-even point, and cost-utility analyses.

Results: A total of 110 WLEs using RL cost a total of AUD$402,281, in addition to the device cost of AUD$77,150. The average additional cost of a surgery delay was AUD$2318. Use of RL reduced the surgery delay rate by 10% (p = 0.029), preventing 11 delays with cost savings of AUD$25,496. No differences were identified in positive margin rates (RL: 11.8% vs. WL: 17.3%, p = 0.25) or re-excision rates (RL: 14.5% vs. WL: 21.8%, p = 0.221). In total, 290 RL cases are needed to break even. The cost of WLE using RL was greater than WL by AUD$567. There was a greater clinical benefit of 1.15 quality-adjusted life-years (QALYs) and an incremental cost-utility ratio of AUD$493 per QALY favouring RL.

Conclusions: Routine use of RL was a more cost-effective intervention than WL. Close to 300 RL cases are likely needed to be performed to recover costs of the medical device.

Clinical trial registration: ACTRN12624000068561.

Keywords: Breast cancer; Cost analysis; Radar localisation; SAVI SCOUT; Wide local excision; Wire localisation.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Aged
  • Australia
  • Breast Neoplasms* / economics
  • Breast Neoplasms* / pathology
  • Breast Neoplasms* / surgery
  • Cost-Benefit Analysis*
  • Female
  • Follow-Up Studies
  • Humans
  • Margins of Excision
  • Mastectomy, Segmental / economics
  • Mastectomy, Segmental / methods
  • Middle Aged
  • Prognosis
  • Prospective Studies
  • Quality-Adjusted Life Years
  • Surgery, Computer-Assisted / economics
  • Surgery, Computer-Assisted / methods

Associated data

  • ANZCTR/ACTRN12624000068561