International consensus is needed on a core outcome set to advance the evidence of best practice in cancer prehabilitation services and research

Anna M Myers; Rachael C Barlow; Gabriele Baldini; Anna M Campbell; Franco Carli; Esther J Carr; Tom Collyer; Gerard Danjoux; June F Davis; Linda Denehy; James Durrand; Chelsia Gillis; Diana M Greenfield; Stuart P Griffiths; Mike Grocott; Liam Humphreys; Sandy Jack; Carol Keen; Denny Z H Levett; Zoe Merchant; John Moore; Susan Moug; William Ricketts; Daniel Santa Mina; John M Saxton; Clare E Shaw; Garry A Tew; Michael Thelwell; Malcolm A West; Robert J Copeland

doi:10.1016/j.bja.2024.02.021

International consensus is needed on a core outcome set to advance the evidence of best practice in cancer prehabilitation services and research

Br J Anaesth. 2024 May;132(5):851-856. doi: 10.1016/j.bja.2024.02.021. Epub 2024 Mar 23.

Authors

Anna M Myers¹, Rachael C Barlow², Gabriele Baldini³, Anna M Campbell⁴, Franco Carli⁵, Esther J Carr⁶, Tom Collyer⁷, Gerard Danjoux⁸, June F Davis⁹, Linda Denehy¹⁰, James Durrand¹¹, Chelsia Gillis¹², Diana M Greenfield¹³, Stuart P Griffiths¹⁴, Mike Grocott¹⁵, Liam Humphreys¹⁶, Sandy Jack¹⁷, Carol Keen¹⁸, Denny Z H Levett¹⁹, Zoe Merchant²⁰, John Moore²¹, Susan Moug²², William Ricketts²³, Daniel Santa Mina²⁴, John M Saxton²⁵, Clare E Shaw²⁶, Garry A Tew²⁷, Michael Thelwell¹⁶, Malcolm A West²⁸, Robert J Copeland¹⁶

Affiliations

¹ Advanced Wellbeing Research Centre, Sheffield Hallam University, Sheffield, UK. Electronic address: A.Myers@shu.ac.uk.
² Cardiff and Vale University Health Board, University Hospital of Wales, Cardiff, UK.
³ Anaesthesiology and Intensive Care Department of Health Sciences, Section of Anaesthesiology, Intensive Care and Pain Medicine, University of Florence, Florence, Italy.
⁴ Edinburgh Napier University, Edinburgh, UK.
⁵ Department of Anaesthesia, McGill University Health Center, Glen Site, Royal Victoria Hospital, Montreal, QC, Canada.
⁶ South Tees NHS Foundation Trust, James Cook University Hospital, Middlesbrough, UK.
⁷ Anaesthetic Department, Harrogate and District NHS Foundation Trust, Harrogate, UK.
⁸ North Yorkshire Academic Alliance of Perioperative Medicine, James Cook University Hospital, Middlesbrough, UK.
⁹ Macmillan Cancer Support, London, UK; Allied Health Solutions, Hadlow, Kent, UK.
¹⁰ Department of Physiotherapy, The University of Melbourne, Melbourne, VIC, Australia; Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.
¹¹ Department of Anaesthesia and Perioperative Medicine, James Cook University Hospital, Middlesbrough, UK.
¹² School of Human Nutrition, McGill University, Montreal, QC, Canada.
¹³ Weston Park Hospital, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK.
¹⁴ Yorkshire Cancer Research, Jacob Smith House, Harrogate, UK.
¹⁵ Faculty of Medicine, University of Southampton, Southampton, UK; Acute Perioperative and Critical Care Theme, NIHR Southampton Biomedical Research Centre, University Hospital Southampton NHS Trust, University of Southampton, Southampton, UK.
¹⁶ Advanced Wellbeing Research Centre, Sheffield Hallam University, Sheffield, UK.
¹⁷ Faculty of Medicine, University of Southampton, Southampton, UK; NIHR Biomedical Research Centre, University Hospital Southampton NHS Trusts, Southampton, UK.
¹⁸ Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK.
¹⁹ Perioperative and Critical Care Theme, NIHR Southampton Biomedical Research Centre, University Hospital Southampton NHS Trust, University of Southampton, Southampton, UK; Integrative Physiology and Critical Illness Group, Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK.
²⁰ Greater Manchester Cancer Alliance, Manchester, UK.
²¹ Department of Anaesthesia and Peri-operative Medicine, Manchester University NHS Foundation Trust, Manchester, UK.
²² Departments of Colorectal Surgery, Royal Alexandra Hospital, Paisley, Scotland, UK.
²³ Respiratory Medicine, Barts Health NHS Trust, St Bartholomew's Hospital, London, UK.
²⁴ Faculty of Kinesiology and Physical Education, University of Toronto, Toronto, ON, Canada; Department of Anaesthesiology and Pain Management, University Health Network, Toronto, ON, Canada.
²⁵ School of Sport, Exercise and Rehabilitation Sciences, University of Hull, Hull, UK.
²⁶ NIHR Biomedical Research Centre at The Royal Marsden and the Institute of Cancer Research, London, UK.
²⁷ York St John University, York, UK.
²⁸ University of Southampton, Faculty of Medicine, Cancer Sciences, University Surgery, Southampton University Hospital NHS Foundation Trust, Southampton, UK.

PMID: 38522964
DOI: 10.1016/j.bja.2024.02.021

Abstract

Prehabilitation aims to optimise patients' physical and psychological status before treatment. The types of outcomes measured to assess the impact of prehabilitation interventions vary across clinical research and service evaluation, limiting the ability to compare between studies and services and to pool data. An international workshop involving academic and clinical experts in cancer prehabilitation was convened in May 2022 at Sheffield Hallam University's Advanced Wellbeing Research Centre, England. The workshop substantiated calls for a core outcome set to advance knowledge and understanding of best practice in cancer prehabilitation and to develop national and international databases to assess outcomes at a population level.

Keywords: cancer; core outcome set; prehabilitation; rehabilitation; surgery.

Publication types

Editorial

MeSH terms

Consensus
Exercise Therapy
Humans
Neoplasms* / surgery
Outcome Assessment, Health Care
Preoperative Exercise*