IL23R G149R Promotes IL-23 Unresponsiveness in Human Memory Th17 Cells

J Invest Dermatol. 2024 Oct;144(10):2317-2320.e2. doi: 10.1016/j.jid.2024.02.032. Epub 2024 Mar 26.
No abstract available

Keywords: G149R; IL23R; Leprosy; Th17 cell; Unresponsiveness.

Publication types

  • Letter

MeSH terms

  • Cells, Cultured
  • Humans
  • Immunologic Memory
  • Interleukin-23* / immunology
  • Interleukin-23* / metabolism
  • Memory T Cells / immunology
  • Memory T Cells / metabolism
  • Receptors, Interleukin* / genetics
  • Receptors, Interleukin* / immunology
  • Receptors, Interleukin* / metabolism
  • Th17 Cells* / immunology
  • Th17 Cells* / metabolism

Substances

  • IL23R protein, human
  • Interleukin-23
  • Receptors, Interleukin