Malvidin Mitigates Sepsis-induced Cardiac Injury by Modulating the TLR4-iNOS-COX-2 Inflammatory Pathway and the Bax/Bcl-2/Cyto-C Mitochondrial Apoptosis Pathway in a p38 MAPK-dependent Manner

Biomed Environ Sci. 2024 Feb 20;37(2):221-227. doi: 10.3967/bes2024.024.
No abstract available

Publication types

  • Letter

MeSH terms

  • Anthocyanins*
  • Apoptosis
  • Cyclooxygenase 2
  • Humans
  • Proto-Oncogene Proteins c-bcl-2 / metabolism
  • Sepsis* / complications
  • Toll-Like Receptor 4
  • bcl-2-Associated X Protein / metabolism
  • p38 Mitogen-Activated Protein Kinases* / metabolism

Substances

  • p38 Mitogen-Activated Protein Kinases
  • bcl-2-Associated X Protein
  • malvidin
  • Toll-Like Receptor 4
  • Cyclooxygenase 2
  • Proto-Oncogene Proteins c-bcl-2
  • TLR4 protein, human
  • Anthocyanins