Ultra-rapid selection of the N74D capsid inhibitor resistance mutation after 3 weeks on lenacapavir

J Antimicrob Chemother. 2024 Jul 1;79(7):1706-1707. doi: 10.1093/jac/dkae115.

Authors

Marc Wirden^{1

2}, Cecile Pouderoux³, Gilles Peytavin⁴, Basma Abdi^{1

2}, Antoine Fayçal^{1

3}, Romain Palich^{1

3}, Marc Antoine Valantin^{1

3}, Sophie Seang^{1

3}, Christine Katlama^{1

3}, Vincent Calvez^{1

2}, Valerie Pourcher^{1

3}, Anne-Geneviève Marcelin^{1

2}

Affiliations

¹ INSERM, Institut Pierre Louis d'Epidémiologie et de Santé Publique (IPLESP), Sorbonne Université, Paris, F75013, France.
² Department of Virology, AP-HP, Pitié Salpêtrière Hospital, Paris, France.
³ Department of Infectious Diseases, AP-HP, Pitié Salpêtrière Hospital, Paris, France.
⁴ Pharmacology Department, AP-HP, Bichat Claude-Bernard University Hospital, Paris, France.

PMID: 38629483
DOI: 10.1093/jac/dkae115

No abstract available

Publication types

Letter
Case Reports
Research Support, Non-U.S. Gov't

MeSH terms

Antiviral Agents / pharmacology
Capsid Proteins / genetics
Drug Resistance, Viral* / genetics
Humans
Mutation*
Quinolones / pharmacology
SARS-CoV-2 / drug effects
SARS-CoV-2 / genetics
Selection, Genetic

Substances

Antiviral Agents
Capsid Proteins
Quinolones

Grants and funding