Etiologies of bloody diarrhea in children presenting with acute gastroenteritis to US emergency departments

Paola Fonseca-Romero; Sharia M Ahmed; Ben J Brintz; D Matthew Vierkant; Jennifer Dien Bard; Daniel M Cohen; Ara Festekjian; Amy L Leber; Jami T Jackson; Neena Kanwar; Chari Larsen; Rangaraj Selvarangan; Kimberle C Chapin; Andrew T Pavia; IMPACT study investigators

doi:10.1101/2024.04.03.24305279

Etiologies of bloody diarrhea in children presenting with acute gastroenteritis to US emergency departments

medRxiv [Preprint]. 2024 Apr 4:2024.04.03.24305279. doi: 10.1101/2024.04.03.24305279.

Authors

Paola Fonseca-Romero^{1

2}, Sharia M Ahmed², Ben J Brintz², D Matthew Vierkant², Jennifer Dien Bard³, Daniel M Cohen⁴, Ara Festekjian³, Amy L Leber⁴, Jami T Jackson⁵, Neena Kanwar⁵, Chari Larsen⁶, Rangaraj Selvarangan⁵, Kimberle C Chapin^{7

8}, Andrew T Pavia^{2

6}; IMPACT study investigators

Affiliations

¹ Department of Pathology, Spencer Fox Eccles School of Medicine, University of Utah, Salt Lake City, UT, USA.
² Department of Internal Medicine, Spencer Fox Eccles School of Medicine, University of Utah, Salt Lake City, UT, USA.
³ Children's Hospital, Los Angeles; Keck School of Medicine, University of Southern California, Los Angeles, CA, US.
⁴ Department of Pediatrics, Nationwide Children's Hospital, Columbus, OH, USA.
⁵ Children's Mercy Hospital, Kansas City, MO, USA.
⁶ Department of Pediatrics, Spencer Fox Eccles School of Medicine, University of Utah, Salt Lake City, UT, USA.
⁷ Deepull, Barcelona, Spain.
⁸ Warren Alpert Medical School, Brown University, Providence, RI, USA.

Abstract

Among 111 children presenting with bloody diarrhea in a multicenter study of molecular testing in US emergency departments, we found viral pathogens in 18%, bacteria in 48%, protozoa in 2%, and no pathogens detected in 38%.

Keywords: Gastroenteritis; antibiotic; bloody diarrhea; multiplex panel; pediatric.

Publication types

Preprint

Abstract

Publication types

Grants and funding