Synthesis of the A/D/E-ring Core Compounds of Maoecrystal V†

Abstract

Synthesis of the A/D/E-ring core compounds of maoecrystal V was achieved. The key Diels-Alder reactions between tricyclic α-methylene lactones and Kitahara-Danishefsky dienes afforded the spirocyclic core compounds in a regioselective and stereoselective manner.

Keywords: Diels-Alder reaction; intramolecular aldol reaction; maoecrystal V; synthesis.