Successful oral midodrine therapy for treatment of refractory postoperative chylothorax in an infant

Cardiol Young. 2024 Jun;34(6):1385-1386. doi: 10.1017/S1047951124025046. Epub 2024 Apr 25.

Abstract

Refractory chylothorax, a postoperative complication of CHD, is difficult to manage and sometimes fatal. Herein, we report the case of a 10-month-old infant with 22-mosaic trisomy and a coarctation complex, who developed refractory chylothorax after cardiac repairs and was successfully treated with midodrine, an oral alpha-1-adrenoreceptor agonist. Midodrine may be used as adjunctive therapy for postoperative refractory chylothorax.

Keywords: CHD; infant; midodrine; postoperative refractory chylothorax.

Publication types

  • Case Reports

MeSH terms

  • Administration, Oral
  • Adrenergic alpha-1 Receptor Agonists / administration & dosage
  • Adrenergic alpha-1 Receptor Agonists / therapeutic use
  • Aortic Coarctation / surgery
  • Chylothorax* / drug therapy
  • Chylothorax* / etiology
  • Humans
  • Infant
  • Male
  • Midodrine* / administration & dosage
  • Midodrine* / therapeutic use
  • Postoperative Complications* / drug therapy
  • Treatment Outcome

Substances

  • Midodrine
  • Adrenergic alpha-1 Receptor Agonists