Using marine mussels to assess the potential ecotoxicological effects of two different commercial microplastics

Mar Pollut Bull. 2024 Jun:203:116441. doi: 10.1016/j.marpolbul.2024.116441. Epub 2024 May 4.

Abstract

Microplastics (MPs) in the aquatic environment pose a serious threat to biota, by being confounded with food. These effects occur in mussels which are filter-feeding organisms. Mussels from the genus Mytilus sp. were used to evaluate the ecotoxicological effects of two MPs, polypropylene (PP) and polyethylene terephthalate (PET), after 4 and 28-days. Measured individual endpoints were condition index and feeding rate; and sub-individual parameters, metabolism of phase I (CYP1A1, CYP1A2 and CYP3A4) and II (glutathione S-transferases - GSTs), and antioxidant defense (catalase - CAT). MPs decreased both condition index (CI) and feeding rate (FR). No alterations occurred in metabolic enzymes, suggesting that these MPs are not metabolized by these pathways. Furthermore, lack of alterations in GSTs and CAT activities suggests the absence of conjugation and oxidative stress. Overall, biochemical markers were not responsive, but non-enzymatic responses showed deleterious effects caused by these MPs, which may be of high ecological importance.

Keywords: Biomarkers; Condition index; Feeding rate; Mytilus sp; Polyethylene terephthalate (PET); Polypropylene (PP).

MeSH terms

  • Animals
  • Catalase / metabolism
  • Ecotoxicology*
  • Environmental Monitoring
  • Glutathione Transferase / metabolism
  • Microplastics* / toxicity
  • Mytilus* / drug effects
  • Oxidative Stress
  • Polyethylene Terephthalates
  • Polypropylenes / toxicity
  • Water Pollutants, Chemical* / toxicity

Substances

  • Water Pollutants, Chemical
  • Microplastics
  • Glutathione Transferase
  • Polypropylenes
  • Polyethylene Terephthalates
  • Catalase