Malassezia-associated skin diseases in the pediatric population

Pediatr Dermatol. 2024 Sep-Oct;41(5):769-779. doi: 10.1111/pde.15603. Epub 2024 May 22.

Abstract

Malassezia are yeast species that commonly colonize healthy skin. However, they have been associated with or implicated in the pathogenesis of numerous skin disorders, particularly in the setting of pediatric populations. In this review, we will focus on several Malassezia-associated skin conditions manifesting in infants, children, and adolescents: pityriasis versicolor, Malassezia folliculitis, infantile and adolescent seborrheic dermatitis, head and neck dermatitis, and neonatal cephalic pustulosis. We examine the literature and provide an overview of these conditions, including clinical presentation in diverse skin colors, diagnosis, risk factors, and treatment and management. Additionally, we summarize and highlight some of the proposed theories on the role of Malassezia spp. in the pathogenesis of these skin conditions.

Keywords: Malassezia; Malassezia folliculitis; head and neck dermatitis; pityriasis versicolor; seborrheic dermatitis.

Publication types

  • Review

MeSH terms

  • Adolescent
  • Child
  • Child, Preschool
  • Dermatitis, Seborrheic / microbiology
  • Dermatomycoses* / diagnosis
  • Dermatomycoses* / microbiology
  • Humans
  • Infant
  • Infant, Newborn
  • Malassezia* / isolation & purification
  • Tinea Versicolor / diagnosis
  • Tinea Versicolor / microbiology