Quinazolines are an important class of heterocyclic compounds that have proven their significance, especially in the field of organic synthesis and medicinal chemistry because of their wide range of biological and pharmacological properties. Thus, numerous synthetic methods have been developed for the synthesis of quinazolines and their derivatives. This review article briefly outlines the new synthetic methods for compounds containing the quinazoline scaffold employing transition metal-catalyzed reactions.
Keywords: C-H activation; cascade reactions; intramolecular dehydrative/dehydrogenative cyclizations; quinazoline heterocycles; transition metal-catalyzed synthesis.