Hemorrhagic and Ecthymatous Varicella in Immunosuppressed Adults: Report of Two Cases

Cureus. 2024 Apr 30;16(4):e59409. doi: 10.7759/cureus.59409. eCollection 2024 Apr.

Abstract

Varicella infection in immunosuppressed adults can be severe with atypical presentation of skin lesions. Hemorrhagic and ecthymatous varicella is a rare entity and can be misdiagnosed due to its atypical presentation. In its severe form, individuals with underlying cell-mediated immunodeficiency disorders have a high risk of developing multiple organ involvement associated with varicella-zoster virus infection. Here, we report two cases of primary varicella with hemorrhagic and ecthymatous skin lesions in adults receiving systemic immunosuppressive drugs for autoimmune disorders. There are only a few case reports on hemorrhagic and ecthymatous varicella. Hence, this case report highlights the atypical presentation of varicella in immunosuppressed adults, which necessitates an early diagnosis and prompt treatment as a lifesaving step.

Keywords: atypical varicella; ecthymatous varicella; hemorrhagic varicella; treatment of varicella in immunosuppressed; varicella in immunosuppressed.

Publication types

  • Case Reports