Using Sex-Specific Polygenic Risk to Prognosticate Coronary Artery Disease in Women

Kaavya Paruchuri; Rohan Bhukar; Sarah Urbut; Yunfeng Ruan; Shriienidhie Ganesh; Darina Postupaka; Pradeep Natarajan

doi:10.1161/JAHA.123.034946

Using Sex-Specific Polygenic Risk to Prognosticate Coronary Artery Disease in Women

J Am Heart Assoc. 2024 Jun 18;13(12):e034946. doi: 10.1161/JAHA.123.034946. Epub 2024 Jun 14.

Authors

Kaavya Paruchuri^{1

2

3}, Rohan Bhukar^{1

2}, Sarah Urbut^{1

2

3

4}, Yunfeng Ruan², Shriienidhie Ganesh^{1

2}, Darina Postupaka^{1

2}, Pradeep Natarajan^{1

2

3

4}

Affiliations

¹ Cardiovascular Research Center Massachusetts General Hospital Boston MA.
² Program in Medical and Population Genetics and Cardiovascular Disease Initiative Broad Institute of Harvard and MIT Cambridge MA.
³ Department of Medicine Harvard Medical School Boston MA.
⁴ Center for Genomic Medicine Massachusetts General Hospital Boston MA.

No abstract available

Keywords: coronary artery disease; polygenic risk score; sex differences; women's health.

MeSH terms

Coronary Artery Disease* / diagnosis
Coronary Artery Disease* / genetics
Female
Genetic Predisposition to Disease
Humans
Male
Multifactorial Inheritance*
Prognosis
Risk Assessment
Risk Factors
Sex Factors