Effect of mineralized dentin matrix on the prognosis of bone defect and retained root after coronectomy

Clin Oral Investig. 2024 Jun 15;28(7):375. doi: 10.1007/s00784-024-05784-2.

Abstract

Objective: To investigate the impact of mineralized dentin matrix (MDM) on the prognosis on bone regeneration and migration of retained roots after coronectomy.

Materials and methods: Patients were divided into three groups based on the type of bone graft after coronectomy: Group C (n = 20, collagen), Group T (n = 20, tricalcium phosphate (TCP) + collagen), and Group D (n = 20, MDM + collagen). CBCT scans, conducted immediately and 6 months after surgery, were analyzed using digital software. Primary outcomes, including changes in bone defect depth and retained root migration distance, were evaluated 6 months after surgery.

Results: After 6 months, both Groups D and T exhibited greater reduction of the bone defect and lesser retained root migration than Group C (p < 0.001). Group D had greater regenerated bone volume in the distal 2 mm (73 mm3 vs. 57 mm3, p = 0.011) and lesser root migration (2.18 mm vs. 2.96 mm, p < 0.001) than Group T. The proportion of completely bone embedded retained roots was also greater in Group D than in Group C (70.0% vs. 42.1%, p = 0.003).

Conclusions: MDM is an appropriate graft material for improving bone defect healing and reducing retained root migration after coronectomy.

Clinical relevance: MDM is an autogenous material prepared chairside, which can significantly improve bone healing and reduce the risk of retained root re-eruption. MDM holds promise as a routine bone substitute material after M3M coronectomy.

Keywords: Bone regeneration; Bone substitutes; Coronectomy; Dentin; Digital technologies.

MeSH terms

  • Adult
  • Bone Regeneration* / drug effects
  • Bone Substitutes / therapeutic use
  • Bone Transplantation / methods
  • Calcium Phosphates* / therapeutic use
  • Collagen* / therapeutic use
  • Cone-Beam Computed Tomography*
  • Dentin*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Prognosis
  • Tooth Crown / surgery
  • Tooth Root / diagnostic imaging
  • Tooth Root / surgery
  • Treatment Outcome

Substances

  • Calcium Phosphates
  • Collagen
  • tricalcium phosphate
  • Bone Substitutes