No differences in outcomes with stopping or continuing antibiotic suppression in periprosthetic joint infections

Daisuke Furukawa; Megan Dunning; Sa Shen; Amy Chang; Jenny Aronson; Derek F Amanatullah; Gina A Suh; Shanthi Kappagoda

doi:10.5194/jbji-9-143-2024

No differences in outcomes with stopping or continuing antibiotic suppression in periprosthetic joint infections

J Bone Jt Infect. 2024 May 14;9(3):143-148. doi: 10.5194/jbji-9-143-2024. eCollection 2024.

Authors

Daisuke Furukawa¹, Megan Dunning¹, Sa Shen², Amy Chang¹, Jenny Aronson¹, Derek F Amanatullah³, Gina A Suh⁴, Shanthi Kappagoda¹

Affiliations

¹ Division of Infectious Diseases and Geographic Medicine, Stanford University, Stanford, California 94304, USA.
² Quantitative Sciences Unit, Stanford University, Stanford, California 94304, USA.
³ Department of Orthopaedic Surgery, Stanford University, Redwood City, California 94063, USA.
⁴ Division of Public Health, Infectious Diseases, and Occupational Medicine, Mayo Clinic, Rochester, Minnesota 55902, USA.

Abstract

The data on long-term antibiotic use following debridement, antibiotics, and implant retention (DAIR) for treatment of periprosthetic joint infections are limited. In this single-center retrospective study, we show that patients with eventual cessation of antibiotic suppression after DAIR had similar outcomes to those who remained on chronic antibiotic suppression.