In July 2023, clade IIb-associated mpox reemerged in Germany at low levels, mainly affecting men who have sex with men. We report a representative case and phylogeny of available genome sequences. Our findings underscore the need for standardized surveillance and indication-based vaccination to limit transmission and help prevent endemicity.
Keywords: Germany; MPXV; Mpox; dermatology; epidemiology; genomic surveillance; monkeypox virus; sexually transmitted infections; surveillance; vaccination; viruses.