Vein diameter, obesity, and rates of recanalization after mechanochemical ablation

J Vasc Surg Venous Lymphat Disord. 2024 Nov;12(6):101935. doi: 10.1016/j.jvsv.2024.101935. Epub 2024 Jun 28.

Abstract

Objective: A large vein diameter is associated with higher recanalization rates after endovenous thermal ablation procedures of the great saphenous vein (GSV) and small saphenous vein (SSV). However, relatively few studies have explored the relationship between vein diameter and recanalization rates after mechanochemical ablation (MOCA).

Methods: We conducted a retrospective review of patients with chronic venous insufficiency who underwent MOCA of the GSV or SSV from 2017 to 2021 at a single hospital. Patients with no follow-up ultrasound examination were excluded. Patients were classified as having a large (≥1 cm) or small (<1 cm) treated vein. The primary outcomes were 2-year recanalization and reintervention of the treated segment.

Results: A total of 186 MOCA procedures during the study period were analyzed. There was no differences in age, gender, history of venous thromboembolic events, use of anticoagulation, obesity, or length of treated segment between the cohorts. Patients with large veins were less likely to have stasis ulcers compared with those with small veins (3.2% vs 21.5%; P < .05 on Fisher exact test). Patients with large veins had a higher incidence of postoperative local complications (24.2% vs 7.2%, P < .05 on χ2 test). A survival analysis with Cox proportional hazards showed no significant difference in recanalization rates with larger vein diameters. However, obesity was found to correlate significantly with recanalization.

Conclusions: A large vein diameter was not associated with higher recanalization rates after MOCA of the GSVs and SSVs. However, obesity was found to correlate with recanalization rates.

Keywords: Endovascular methods; Mechanochemical ablation; Obesity; Treatment failure; Venous insufficiency.

MeSH terms

  • Ablation Techniques / adverse effects
  • Adult
  • Aged
  • Chronic Disease
  • Endovascular Procedures / adverse effects
  • Female
  • Humans
  • Male
  • Middle Aged
  • Obesity* / complications
  • Postoperative Complications / etiology
  • Retrospective Studies
  • Risk Assessment
  • Risk Factors
  • Saphenous Vein* / diagnostic imaging
  • Saphenous Vein* / surgery
  • Time Factors
  • Treatment Outcome
  • Venous Insufficiency* / diagnostic imaging
  • Venous Insufficiency* / surgery
  • Venous Insufficiency* / therapy