KPC-85, a carbapenemase-producing and ceftazidime-avibactam-resistant KPC-3 variant found in Klebsiella pneumoniae ST512 in the Netherlands

Int J Antimicrob Agents. 2024 Sep;64(3):107271. doi: 10.1016/j.ijantimicag.2024.107271. Epub 2024 Jul 11.
No abstract available

Publication types

  • Letter

MeSH terms

  • Anti-Bacterial Agents* / pharmacology
  • Azabicyclo Compounds* / pharmacology
  • Bacterial Proteins* / genetics
  • Bacterial Proteins* / metabolism
  • Ceftazidime* / pharmacology
  • Drug Combinations*
  • Drug Resistance, Multiple, Bacterial / genetics
  • Humans
  • Klebsiella Infections* / drug therapy
  • Klebsiella Infections* / microbiology
  • Klebsiella pneumoniae* / drug effects
  • Klebsiella pneumoniae* / enzymology
  • Klebsiella pneumoniae* / genetics
  • Klebsiella pneumoniae* / isolation & purification
  • Microbial Sensitivity Tests
  • Netherlands
  • beta-Lactamases* / genetics
  • beta-Lactamases* / metabolism

Substances

  • Anti-Bacterial Agents
  • avibactam, ceftazidime drug combination
  • Azabicyclo Compounds
  • Bacterial Proteins
  • beta-lactamase KPC-3, Klebsiella pneumoniae
  • beta-Lactamases
  • carbapenemase
  • Ceftazidime
  • Drug Combinations