Acute Leriche Syndrome Mimicking Spinal Cord Infarction: A Case Report

Case Rep Neurol. 2024 May 24;16(1):148-153. doi: 10.1159/000539456. eCollection 2024 Jan-Dec.

Abstract

Introduction: Acute Leriche syndrome is a rare but potentially life-threatening condition. Pain, pallor, and coldness of the lower extremities serve as clues for suspecting Leriche syndrome. However, the absence of these findings may pose a diagnostic challenge.

Case presentation: An 83-year-old man presented at our emergency department with a complaint of sudden-onset paraparesis. Initially, spinal cord infarction was suspected due to clinical course and neurological findings, but thoracolumbar MRI showed normal findings. On admission, symptoms associated with aortoiliac occlusion were not present, except for muscle atrophy in the thigh. CT angiography revealed aortoiliac occlusion, leading to a diagnosis of Leriche syndrome.

Conclusion: Leriche syndrome should be considered as a potential differential diagnosis in patients with acute paraparesis. Muscle atrophy of the lower limbs disproportionate to the clinical course may be the clue for suspecting acute Leriche syndrome with symptoms related to atherosclerotic occlusion which are inconspicuous.

Keywords: Contrast-enhanced computed tomography; Leriche syndrome; Muscle atrophy; Spinal cord infarction.

Publication types

  • Case Reports

Grants and funding

This study was supported by Japan Society for the Promotion of Science, Grants-in-Aid for Young Scientists (JP22K15738).