The escalating rates of gonorrhea globally are associated with higher numbers of disseminated gonococcal infection (DGI). Expression of the PorB1A allele of the major outer membrane porin protein, PorB, is associated with DGI. This meta-analysis shows that the odds of PorB1A strains to disseminate is 20.53 compared to PorB1B isolates.
Keywords: Neisseria gonorrhoeae; PorB; disseminated gonococcal infection; gonorrhea; serotype.
© The Author(s) 2024. Published by Oxford University Press on behalf of Infectious Diseases Society of America.