Antiprotozoal, Anthelmintic and Antivectorial Activities of Titanium Dioxide Nanoparticles

Thainá Silva Bologna; Isabella de Oliveira Ferrato de Sousa; José Rodrigues do Carmo Neto; Thaís Amanda de Lima Nunes; Beatriz Sodré Matos; Priscilla Elias Ferreira da Silva; Rhanoica Oliveira Guerra; Pablo Igor Ribeiro Franco; Juliana Reis Machado; Anielle Christine Almeida Silva; Marcos Vinicius da Silva

doi:10.2174/0109298673295600240725060349

Antiprotozoal, Anthelmintic and Antivectorial Activities of Titanium Dioxide Nanoparticles

Curr Med Chem. 2024 Jul 26. doi: 10.2174/0109298673295600240725060349. Online ahead of print.

Affiliations

¹ Department of Microbiology, Immunology and Parasitology, Institute of Biological and Natural Sciences of Federal University of Triângulo Mineiro, Uberaba, Minas Gerais, Brazil.
² Department of Bioscience and Technology, Institute of Tropical Pathology and Public Health, Federal University of Goias, Goiania, GO, Brazil.
³ Department of Cell Biology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, SP, Brazil.
⁴ Department of General Pathology, Federal University of Triângulo Mineiro, Uberaba, Minas Gerais, Brazil.
⁵ Laboratory of New Nanostructured and Functional Materials, Physics Institute, Federal University of Alagoas, Maceió, Alagoas, Brazil.

PMID: 39069809
DOI: 10.2174/0109298673295600240725060349

Abstract

Nanotechnology has been established as a promising alternative for treating a myriad of disease-causing microorganisms that pose threats to human health. The utilization of nanoparticles (NPs) emerges as a strategy to enhance the therapeutic arsenal against these diseases, especially given the tendency of many pathogens to develop resistance to conventional medications. Notably, titanium dioxide nanoparticles (TiO2NPs) have garnered attention for their multifaceted biomedical applications, encompassing antibacterial, antifungal, antiviral, anticancer, antioxidant, and drug delivery properties. This review focuses on the cutting-edge potential of TiO2NPs against helminths, protozoa, and vectors, underscoring their pivotal role in combating these health-threatening agents.

Keywords: Nanocomposite; antiprotozoal and anthelmintic.; nanoparticles; titanium dioxide; treatment.