Rectal Lymphogranuloma Venereum Among Men Who Have Sex With Men: 7 Versus 21 Days Doxycycline Effectiveness

Sex Transm Dis. 2024 Dec 1;51(12):772-774. doi: 10.1097/OLQ.0000000000002065. Epub 2024 Aug 6.

Abstract

This is a retrospective study on men who have sex with men (MSM) diagnosed with rectal lymphogranuloma venereum (LGV), treated with 7 or 21 days of doxycycline between 2015 and 2022. Overall, 143 MSM were included: 58 (41%) had LGV. One hundred percent of microbiologic cure was found among MSM with symptomatic or asymptomatic LGV treated with 7 and 21 days of doxycycline.

MeSH terms

  • Adult
  • Anti-Bacterial Agents* / administration & dosage
  • Anti-Bacterial Agents* / pharmacology
  • Anti-Bacterial Agents* / therapeutic use
  • Chlamydia trachomatis / isolation & purification
  • Doxycycline* / administration & dosage
  • Doxycycline* / therapeutic use
  • Homosexuality, Male*
  • Humans
  • Lymphogranuloma Venereum* / drug therapy
  • Male
  • Middle Aged
  • Rectal Diseases / drug therapy
  • Rectal Diseases / microbiology
  • Retrospective Studies
  • Sexual and Gender Minorities
  • Treatment Outcome

Substances

  • Doxycycline
  • Anti-Bacterial Agents