Characterization of atrial arrhythmias following mitral valve repair: Incidence and risk factors

J Cardiovasc Electrophysiol. 2024 Oct;35(10):1972-1980. doi: 10.1111/jce.16390. Epub 2024 Aug 8.

Abstract

Objectives: This study aims to investigate the occurrence, type and correlation of early and late atrial arrhythmias following mitral valve repair in patients with no preoperative history of atrial arrhythmias.

Methods: Patients undergoing mitral valve (MV) repair for degenerative disease were included. Early and late postoperative electrocardiograms were evaluated for the incidence and type of atrial arrhythmia (atrial fibrillation [AF] or atrial tachycardia [AT]).

Results: The 192 patients were included. Early atrial arrhythmias occurred in 100/192 (52.1%) patients; AF in 61 (31.8%) patients, early AT in 15 (7.8%) and both in 24 (12.5%). In total 89% of patients were discharged in sinus rhythm. During a follow-up time of 7.3 years, 14 patients (7.3%) died and 49 (25.5%) patients developed late atrial arrhythmias. At 10 years, the cumulative incidence of any late atrial arrhythmia, with death as competing risk, was 64% (95% confidence interval [CI] = 55%-72%). On Fine-Gray model analysis, only early postoperative AF lasting >24 h was related to the development of late AF (hazard ratio 5.99, 95% CI = 1.78%-20.10%, p = .004). Early postoperative ATs were related to the development of late tachycardias, independent of their duration (<24 h hazard ratio 4.25, 95% CI = 1.89-9.57, p = .001 and >24 h hazard ratio 3.51, 95% CI = 1.65-7.46, p = .001).

Conclusions: Early and late atrial arrhythmias were common after MV repair surgery. Only early postoperative AF lasting >24 h was a risk factor for the occurrence of late AF. Conversely, any postoperative AT was correlated to the development of late ATs.

Keywords: atrial arrhythmia; atrial fibrillation; cardiac surgery; mitral valve repair.

MeSH terms

  • Action Potentials
  • Adult
  • Aged
  • Atrial Fibrillation* / diagnosis
  • Atrial Fibrillation* / epidemiology
  • Atrial Fibrillation* / mortality
  • Atrial Fibrillation* / physiopathology
  • Female
  • Heart Rate
  • Humans
  • Incidence
  • Male
  • Middle Aged
  • Mitral Valve Insufficiency / epidemiology
  • Mitral Valve Insufficiency / mortality
  • Mitral Valve Insufficiency / physiopathology
  • Mitral Valve Insufficiency / surgery
  • Mitral Valve* / physiopathology
  • Mitral Valve* / surgery
  • Retrospective Studies
  • Risk Assessment
  • Risk Factors
  • Tachycardia, Supraventricular / diagnosis
  • Tachycardia, Supraventricular / epidemiology
  • Tachycardia, Supraventricular / physiopathology
  • Time Factors
  • Treatment Outcome