Patients ask and pathologists answer: ten questions around prostate cancer grading

Alessia Cimadamore; Liang Cheng; Antonio Lopez-Beltran; Carmine Franzese; Gianluca Giannarini; Alessandro Crestani; Eamonn T Rogers; Rodolfo Montironi

doi:10.1007/s00428-024-03891-9

Patients ask and pathologists answer: ten questions around prostate cancer grading

Virchows Arch. 2024 Aug 17. doi: 10.1007/s00428-024-03891-9. Online ahead of print.

Authors

Alessia Cimadamore¹, Liang Cheng², Antonio Lopez-Beltran³, Carmine Franzese⁴, Gianluca Giannarini⁴, Alessandro Crestani⁴, Eamonn T Rogers⁵, Rodolfo Montironi⁶

Affiliations

¹ Institute of Pathological Anatomy, Department of Medicine, University of Udine, Udine, Italy.
² Department of Pathology and Laboratory Medicine, Department of Surgery (Urology), Brown University Warren Alpert Medical School, Lifespan Health, and the Legorreta Cancer Center at Brown University, Providence, RI, USA.
³ Department of Surgery, Cordoba University Medical School, Cordoba, Spain.
⁴ Urology Unit, University Hospital, Ospedale Santa Maria Della Misericordia, Udine, Italy.
⁵ Department of Urology, National University of Ireland Galway, Galway, Ireland.
⁶ Molecular Medicine and Cell Therapy Foundation, c/o Polytechnic University of the Marche Region, Via Tronto 10, 60126, Ancona, Italy. rodolfo.montironi51@gmail.com.

PMID: 39153109
DOI: 10.1007/s00428-024-03891-9

Abstract

Pathologists have closely collaborated with clinicians, mainly urologists, to update the Gleason grading system to reflect the current practice and approach in prostate cancer diagnosis, prognosis, and treatment. This has led to the development of what is called patient advocacy and patient information. Ten common questions asked by patients to pathologists concerning PCa grading and the answers given by the latter are reported.

Keywords: Gleason score; Grade group; Patient advocacy; Patient information; Prostate cancer; Uropathology.