Pleural effusions identified by thoracic ultrasound predict poor quality of life in patients with acute decompensated heart failure

Heart Lung. 2024 Nov-Dec:68:279-283. doi: 10.1016/j.hrtlng.2024.08.008. Epub 2024 Aug 17.

Abstract

Introduction: Pleural effusion (PE) is a common manifestation of acute decompensated heart failure (ADHF); however, its influence on the quality of life (QoL) is unknown.

Objectives: To identify whether PE detected using thoracic ultrasound (TUS) is associated with poorer QoL in patients with ADHF and a reduced ejection fraction (≤40 %).

Methods: We conducted a prospective, longitudinal, descriptive, observational, single-center study at a university hospital in Mexico. We included participants with a reduced left ventricular ejection fraction who were admitted for ADHF. We performed TUS and the Minnesota Living with Heart Failure Questionnaire (MLHFQ) within the first 48 h of hospitalization.

Results: Forty patients with ADHF (30 males and 10 females; mean age, 51.24 ± 16.942 years) were included in this study. The participants were categorized into two groups: those with (n = 25, 62.5 %) or without (n = 15, 37.5 %) PE on TUS. We found a statistically significant association between the presence of PEs and a worse perception of QoL. The mean MLHFQ score in the group of patients with PEs was 40 points, compared to 12 points in the group without PEs (p < 0.001). Poorer QoL was associated with a higher quantity of pleural fluid, as evidenced by the greater number of intercostal spaces occupied by the PE (p < 0.001).

Conclusions: Patients with ADHF and a reduced ejection fraction who present with PE have a worse perception of QoL than patients without PE.

Keywords: Heart failure; Minnesota Living with Heart Failure Questionnaire; Pleural effusion; Quality of life; Thoracic ultrasound.

Publication types

  • Observational Study

MeSH terms

  • Acute Disease
  • Adult
  • Aged
  • Female
  • Heart Failure* / complications
  • Heart Failure* / physiopathology
  • Heart Failure* / psychology
  • Humans
  • Male
  • Mexico
  • Middle Aged
  • Pleural Effusion* / physiopathology
  • Pleural Effusion* / psychology
  • Prospective Studies
  • Quality of Life* / psychology
  • Stroke Volume / physiology
  • Surveys and Questionnaires
  • Ultrasonography* / methods