Mucins protect against Streptococcus pneumoniae virulence by suppressing pneumolysin expression

J Clin Invest. 2024 Aug 22;134(19):e182769. doi: 10.1172/JCI182769.

Jade Bath^{1

2}, Elisabet Bjånes³, Cengiz Goekeri⁴, Jeff Hsiao^{1

5}, Deniz Uzun¹, Geraldine Nouailles⁴, Victor Nizet^{3

6}, Katharina Ribbeck¹

¹ Department of Biological Engineering and.
² Microbiology Graduate Program, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.
³ Division of Host-Microbe Systems and Therapeutics, Department of Pediatrics, UCSD, La Jolla, California, USA.
⁴ Department of Infectious Diseases, Respiratory Medicine and Critical Care, Charite - Universitätsmedizin Berlin, Berlin, Germany.
⁵ Ragon Institute of MGH, MIT, and Harvard, Cambridge, Massachusetts, USA.
⁶ Skaggs School of Pharmacy and Pharmaceutical Sciences, UCSD, La Jolla, California, USA.

No abstract available

Keywords: Bacterial infections; Glycobiology; Infectious disease; Microbiology.

MeSH terms

Institute for Collaborative Biotechnologies