Venetoclax with hypomethylating agents versus intensive chemotherapy in newly diagnosed acute myeloid leukemia with myelodysplasia related changes: A propensity score-matched analysis based on International Consensus Classification

Chao-Ling Wan; Yu-Qing Liu; Fang-Tong Liu; Yuan-Hong Huang; Han-Yu Cao; Si-Man Huang; Kai-Wen Tan; Shuai-Shuai Ge; Miao Wang; Mei-Jing Liu; Zi-Hao Wang; Zheng Li; Sheng-Li Xue; Hai-Ping Dai

doi:10.1038/s41408-024-01130-7

Venetoclax with hypomethylating agents versus intensive chemotherapy in newly diagnosed acute myeloid leukemia with myelodysplasia related changes: A propensity score-matched analysis based on International Consensus Classification

Blood Cancer J. 2024 Aug 23;14(1):144. doi: 10.1038/s41408-024-01130-7.

Authors

Chao-Ling Wan^#^{1

2}, Yu-Qing Liu^#³, Fang-Tong Liu^#^{1

2}, Yuan-Hong Huang^{1

2}, Han-Yu Cao^{1

2}, Si-Man Huang^{1

2}, Kai-Wen Tan^{1

2}, Shuai-Shuai Ge^{1

2}, Miao Wang^{1

2}, Mei-Jing Liu^{1

2}, Zi-Hao Wang^{1

2}, Zheng Li^{4

5}, Sheng-Li Xue^{6

7}, Hai-Ping Dai^{8

9}

Affiliations

¹ National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Suzhou, China.
² Institute of Blood and Marrow Transplantation, Collaborative Innovation Center of Hematology, Soochow University, Suzhou, China.
³ Changshu Hospital Affiliated to Soochow University, Changshu No.1 People's Hospital, Changshu, Jiangsu Province, China.
⁴ National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Suzhou, China. lzheng@suda.edu.cn.
⁵ Institute of Blood and Marrow Transplantation, Collaborative Innovation Center of Hematology, Soochow University, Suzhou, China. lzheng@suda.edu.cn.
⁶ National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Suzhou, China. slxue@suda.edu.cn.
⁷ Institute of Blood and Marrow Transplantation, Collaborative Innovation Center of Hematology, Soochow University, Suzhou, China. slxue@suda.edu.cn.
⁸ National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Suzhou, China. daihaiping8@126.com.
⁹ Institute of Blood and Marrow Transplantation, Collaborative Innovation Center of Hematology, Soochow University, Suzhou, China. daihaiping8@126.com.

^# Contributed equally.

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Adult
Aged
Aged, 80 and over
Antineoplastic Combined Chemotherapy Protocols / adverse effects
Antineoplastic Combined Chemotherapy Protocols / therapeutic use
Bridged Bicyclo Compounds, Heterocyclic* / administration & dosage
Bridged Bicyclo Compounds, Heterocyclic* / therapeutic use
Female
Humans
Leukemia, Myeloid, Acute* / drug therapy
Male
Middle Aged
Myelodysplastic Syndromes* / diagnosis
Myelodysplastic Syndromes* / drug therapy
Propensity Score*
Sulfonamides* / administration & dosage
Sulfonamides* / therapeutic use

Substances

venetoclax
Bridged Bicyclo Compounds, Heterocyclic
Sulfonamides

Publication types

MeSH terms

Substances

Grants and funding