Factors associated with COVID-19 death in pregnant women hospitalized in Intensive Care Units

Rev Bras Enferm. 2024 Aug 26;77(5):e20230172. doi: 10.1590/0034-7167-2023-0172. eCollection 2024.
[Article in English, Portuguese]

Abstract

Objectives: to evaluate the factors associated with COVID-19 death in pregnant women hospitalized in Intensive Care Units in Brazil.

Methods: this ecological study was conducted using secondary data from Brazilian pregnant women with COVID-19 hospitalized in Intensive Care Units between March 2020 and March 2022. Univariate analysis and logistic regression were employed.

Results: out of 3,547 pregnant women with COVID-19 hospitalized in Intensive Care Units, 811 died (22.8%). It was found that lack of COVID-19 vaccination (OR: 2.73; 95% CI: 1.83; 4.04), dyspnea (OR: 1.73; 95% CI: 1.17; 2.56), obesity (OR: 1.51; 95% CI: 1.05; 2.17), chronic cardiovascular disease (OR: 1.65; 95% CI: 1.14; 2.38), and non-white race/color (OR: 1.29; 95% CI: 1.00; 1.66) were independently and significantly associated with death.

Conclusions: it is concluded that vaccination status, presence of comorbidities, and clinical and ethnic-racial characteristics are associated with COVID-19 death in pregnant women hospitalized in Intensive Care Units in Brazil.

Objetivos:: evaluar los factores relacionados al óbito por COVID-19 en embarazadas hospitalizadas en Unidad de Cuidados Intensivos en Brasil.

Métodos:: se trata de un estudio ecológico realizado con datos secundarios de embarazadas brasileñas con COVID-19 hospitalizadas en Unidad de Cuidados Intensivos, entre marzo de 2020 y marzo de 2022. Empleado análisis univariado y regresión logística.

Resultados:: de 3.547 embarazadas con COVID-19 hospitalizadas en Unidad de Cuidados Intensivos, 811 evolucionaron a óbito (22,8%). Evidenciado que la no vacunación contra la COVID-19 (OR: 2,73; IC95: 1,83;4,04), disnea (OR: 1,73; IC95:1,17;2,56), obesidad (OR: 1,51; IC95: 1,05;2,17), enfermedad cardiovascular crónica (OR: 1,65; IC95: 1,14;2,38) y la raza/color no blanca (OR: 1,29; IC95: 1,00;1,66) se relacionaron de manera independiente y significante al óbito.

Conclusiones:: concluido que el estado de vacunación, presencia de comorbilidades y características clínicas y étnico-raciales están relacionadas al óbito por COVID-19 en embarazadas hospitalizadas en Unidad de Cuidados Intensivos en Brasil.

MeSH terms

  • Adult
  • Brazil / epidemiology
  • COVID-19* / mortality
  • Comorbidity
  • Female
  • Hospitalization / statistics & numerical data
  • Humans
  • Intensive Care Units* / organization & administration
  • Intensive Care Units* / statistics & numerical data
  • Pregnancy
  • Pregnancy Complications, Infectious* / epidemiology
  • Pregnancy Complications, Infectious* / mortality
  • Pregnant Women
  • Risk Factors
  • SARS-CoV-2