Assessment of microplastics in human stool: A pilot study investigating the potential impact of diet-associated scenarios on oral microplastics exposure

Sci Total Environ. 2024 Nov 15:951:175825. doi: 10.1016/j.scitotenv.2024.175825. Epub 2024 Aug 27.

Abstract

As emerging contaminants microplastic particles have become of particular relevance as they are widely present in the environment and of potential concern to human health. Humans are exposed through different routes, with oral intake and inhalation being the most significant. Dietary intake substantially contributes to oral exposure, although data is still lacking. This first-of-its-kind pilot study investigates the influence of different plastic use and food consumption scenarios (normal, low, high) on microplastic content in stool reflecting oral intake by performing an intervention study with fifteen volunteers. Stool samples were analyzed for ten different plastic types in three size fractions including 5-50 μm (qualitative), 50-500 μm and 500-5000 μm (quantitative). In all samples, microplastic particles were detected with median concentrations up to 3.5 particles/g stool in the size fraction 50-500 μm. Polyethylene was the most frequently detected polymer type. The different scenarios did not result in a consistent pattern of microplastics, however, the use of plastics for food packaging and preparation, and the consumption of highly processed food were statistically significantly associated with microplastics content in stool. These results provide initial findings that contribute to filling current knowledge gaps and pave the way for further research.

Keywords: Diet; FTIR; Human feces; Intervention study; Plastic.

MeSH terms

  • Adult
  • Diet / statistics & numerical data
  • Dietary Exposure / analysis
  • Dietary Exposure / statistics & numerical data
  • Environmental Exposure / analysis
  • Environmental Exposure / statistics & numerical data
  • Environmental Monitoring
  • Feces* / chemistry
  • Humans
  • Male
  • Microplastics* / analysis
  • Pilot Projects
  • Plastics / analysis

Substances

  • Microplastics
  • Plastics