Detection of Brucella S19 Vaccine Strain DNA in Domestic and Wild Ungulates from Brazilian Pantanal

Curr Microbiol. 2024 Aug 30;81(10):333. doi: 10.1007/s00284-024-03847-x.

Abstract

The Pantanal region, the largest floodplain in the world, has a huge biodiversity and is an important livestock center. Bovine brucellosis has been reported in the region over the last three decades, posing implications for cattle industry as well as for the maintenance of biodiversity. We aimed to investigate the presence of B. abortus S19 vaccine strain DNA in unvaccinated domestic and wild ungulates from the Brazilian Pantanal. Fifty-two heifers, 63 ovine, 24 domestic pigs, 28 feral pigs, and three Pampas deer were sampled. Brucella spp. was detected through bcsp31 PCR of blood samples in 45.3% (77/170) of the sampled animals, of which 36.4% (28/77) showed positivity in ery PCR corresponding to B. abortus S19 strain. Feral pigs presented the highest occurrence of positive samples in bcsp31 PCR (75%), followed by ovine (47.6%), domestic pigs (41.7%), and unvaccinated heifers (30.8%). We did not observe positivity in Pampas deer. Our results strongly suggest that vaccination against bovine brucellosis may promote spill-over of B. abortus S19 strain in the Pantanal region. Moreover, our data indicate that wild strains of Brucella circulates in the Pantanal Biome.

Keywords: Brucellosis; Cattle; Pantanal; Vaccination; Wildlife.

MeSH terms

  • Animals
  • Animals, Domestic / microbiology
  • Animals, Wild* / microbiology
  • Brazil
  • Brucella Vaccine / genetics
  • Brucella Vaccine / immunology
  • Brucella abortus / classification
  • Brucella abortus / genetics
  • Brucella abortus / immunology
  • Brucella abortus / isolation & purification
  • Brucellosis* / microbiology
  • Brucellosis* / veterinary
  • Cattle
  • DNA, Bacterial* / genetics
  • Deer* / microbiology
  • Sheep
  • Swine

Substances

  • DNA, Bacterial
  • Brucella Vaccine