tDCS for the treatment of negative symptoms in youth at clinical-high-risk for psychosis: A feasibility study

Psychiatry Res Neuroimaging. 2024 Oct:344:111879. doi: 10.1016/j.pscychresns.2024.111879. Epub 2024 Aug 30.

Abstract

Negative symptoms are often found in youth at clinical high risk (CHR) for psychosis. The present study explored the feasibility of using tDCS in conjunction with CBT in the treatment of negative symptoms in 5 youths at CHR. We sought to determine whether the protocol was feasible given the requirement for repeated visits over a three-week period, and to determine if measures of neurobiological change could be included, both acutely and following three weeks of stimulation. The results from this study suggest that the protocol is feasible for these youth, and the inclusion of MRI scanning sessions yielded good quality data.

MeSH terms

  • Adolescent
  • Cognitive Behavioral Therapy / methods
  • Feasibility Studies*
  • Female
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Psychotic Disorders* / diagnostic imaging
  • Psychotic Disorders* / therapy
  • Risk
  • Transcranial Direct Current Stimulation* / methods
  • Treatment Outcome
  • Young Adult