Echocardiographic assessment of right ventricular function and right ventriculoarterial coupling in tricuspid regurgitation

Int J Cardiovasc Imaging. 2024 Nov;40(11):2247-2259. doi: 10.1007/s10554-024-03215-7. Epub 2024 Sep 3.

Abstract

Echocardiographic evaluation of the cardiopulmonary unit is difficult in case of tricuspid regurgitation (TR) and combined echocardiographic parameters could be useful. This study aimed to assess the variation of simple and combined echocardiographic parameters analysing the cardiopulmonary unit according to the severity of TR. TR was graded according to Hahn's classification in 179 patients. Classical morphological, function and load parameters analysing right ventricle were assessed. Combined parameters of function and load; morphology and load; and morphology-load-function index were calculated. We used ROC curve analysis to analyze the diagnostic value of echocardiographic parameters to predict potential high or low surgical risk of mortality according to TRISCORE in 82 patients. Simple parameters were significatively different among groups with a nonlinear progression between the 5 levels of severity of TR. Combined parameters were also significatively different among groups. Among them, myomechanical index (MMI = RV-RA mean pressure gradient x RVFWS/indexed RAED area × 10-2) and morphology-load-function index (MLF = RVED length/area x TR TVI x RVFWS) had a linear progression between the 5 groups and had the best predictive value for TRISCORE high and low risk. Combined parameters are relevant to evaluate cardiopulmonary unit in patients with various degrees of TR, especially when combining morphology, function, and load parameters, and are potentially interesting in their prognostic assessment, as shown by the good predictive value for TRISCORE risk.

Keywords: Echocardiography; Prognosis; Right ventricle; Tricuspid regurgitation; Ventriculoarterial coupling.

MeSH terms

  • Aged
  • Aged, 80 and over
  • Area Under Curve
  • Atrial Function, Right
  • Echocardiography, Doppler
  • Female
  • Humans
  • Male
  • Middle Aged
  • Predictive Value of Tests*
  • Prognosis
  • Reproducibility of Results
  • Retrospective Studies
  • Risk Factors
  • Severity of Illness Index*
  • Tricuspid Valve Insufficiency* / diagnostic imaging
  • Tricuspid Valve Insufficiency* / physiopathology
  • Tricuspid Valve* / diagnostic imaging
  • Tricuspid Valve* / physiopathology
  • Ventricular Dysfunction, Right / diagnostic imaging
  • Ventricular Dysfunction, Right / etiology
  • Ventricular Dysfunction, Right / physiopathology
  • Ventricular Function, Right*