The presence of cognitive impairments in the acute phase of traumatic upper limb injuries: A cross-sectional observational study

Neuroscience. 2024 Nov 1:559:181-187. doi: 10.1016/j.neuroscience.2024.09.003. Epub 2024 Sep 7.

Abstract

Objectives: The purpose of this study was to investigate the association between cognitive impairments and traumatic upper limb injuries of the acute phase.

Material and methods: A cross-sectional observational study was conducted with three groups: a nerve-injury group, a without nerve injury group, and a control group (uninjured participants). Demographic characteristics (e.g. age, sex, body mass index, and education) and traumatic characteristics (duration since injury, injury side, pain, light touch sensation, hand motor function) were recorded. Short-term memory and executive functions were assessed using Rey Auditory and Verbal Learning Test (RAVLT) and Stroop Color and Word Test (SCWT, including SIECT and SIECN), respectively.

Results: The study comprised 43 participants in the nerve-injury group, 30 participants in the group without nerve injury, and 104 participants in the control group. Generalized linear model was applied to explore the difference of cognitive functions among three groups with impactors. Significantly poorer performance on the RAVLT was observed in the nerve-injury group compared to the other two groups, and lower score of SIECT in nerve-injury group was lower compared to the control group. However, there was no significant difference of SIECN among three groups. In addition, traumatic characteristics did not significantly impact RAVLT and SIECT (p > 0.05) in all injured participants.

Conclusion: Traumatic nerve injury to the upper limb appears to be associated with both short-term memory and executive function impairment, whereas musculoskeletal injuries without nerve damage showed no cognitive impairment. Therefore, it is important to monitor cognitive function following upper limb nerve injuries.

Keywords: Cognitive functions; Executive function; Hand injury; Memory; Upper limb injury.

Publication types

  • Observational Study

MeSH terms

  • Adult
  • Cognitive Dysfunction* / etiology
  • Cognitive Dysfunction* / physiopathology
  • Cross-Sectional Studies
  • Executive Function / physiology
  • Female
  • Humans
  • Male
  • Memory, Short-Term / physiology
  • Middle Aged
  • Neuropsychological Tests
  • Upper Extremity* / physiopathology
  • Young Adult