Reported mpox cases in England continued at a low but steady frequency during 2023. Of 137 cases reported in 2023, approximately half were acquired overseas and half were in vaccinated persons. Estimated effectiveness of 2-dose vaccine was 80%, and no vaccinated mpox patient was hospitalized.
Keywords: England; GBMSM; epidemiology; men who have sex with men; monkeypox virus; mpox; surveillance; vaccine effectiveness; viruses.