Immune responses to cells and proteins after hematopoietic stem cell gene therapy for inherited diseases: A cause for concern

Mol Ther. 2024 Oct 2;32(10):3201-3202. doi: 10.1016/j.ymthe.2024.09.014. Epub 2024 Sep 17.

Authors

Nathan Jeffreys¹, Robert Wynn²

Affiliations

¹ Blood and Marrow Transplant Programme, Royal Manchester Children's Hospital, Manchester, UK.
² Blood and Marrow Transplant Programme, Royal Manchester Children's Hospital, Manchester, UK. Electronic address: robert.wynn@mft.nhs.uk.

PMID: 39293430
PMCID: PMC11489541 (available on 2025-10-02)
DOI: 10.1016/j.ymthe.2024.09.014

No abstract available

Publication types

Editorial

MeSH terms

Animals
Genetic Diseases, Inborn* / genetics
Genetic Diseases, Inborn* / immunology
Genetic Diseases, Inborn* / therapy
Genetic Therapy* / methods
Hematopoietic Stem Cell Transplantation* / methods
Hematopoietic Stem Cells* / metabolism
Humans