Severe poisoning with semi-synthetic cannabinoids

Ugeskr Laeger. 2024 Sep 9;186(37):V04240241. doi: 10.61409/V04240241.
[Article in Danish]

Abstract

Recently, semi-synthetic cannabinoids have entered the illegal market and are produced to mimic the psychoactive effects of tetrahydrocannabinol (THC). This is a case report of a 19-year-old man, who was hospitalized due to severe sedation, hypotension and tachy- and bradycardia after ingestion of the semi-synthetic cannabinoids hexahydrocannabinol (HHC) and hexahydrocannabiphorol (HHC-P) mixed in food. HHC-P, HHC and metabolites were identified in blood samples. The amount of semi-synthetic cannabinoids in illegal products can be high, which can explain the described prolonged clinical effects.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Bradycardia / chemically induced
  • Cannabinoids* / poisoning
  • Dronabinol / blood
  • Dronabinol / poisoning
  • Humans
  • Hypotension / chemically induced
  • Male
  • Tachycardia / chemically induced
  • Young Adult

Substances

  • Cannabinoids
  • Dronabinol