Glaucoma: Current and New Therapeutic Approaches

Biomedicines. 2024 Sep 3;12(9):2000. doi: 10.3390/biomedicines12092000.

Abstract

Glaucoma is identified by the loss of retinal ganglion cells (RGCs). The primary approach to managing glaucoma is to control intraocular pressure (IOP). Lately, there has been an increasing focus on neuroprotective therapies for glaucoma because of the limited effectiveness of standard methods in reducing IOP and preventing ongoing vision deterioration in certain glaucoma patients. Various drug-based techniques with neuroprotective properties have demonstrated the ability to decrease the mortality of retinal ganglion cells. This study will analyze the currently recommended drug-based techniques for neuroprotection in the prospective treatment of glaucoma.

Keywords: excitotoxicity; glaucoma therapeutic approaches; neurodegeneration; neuroinflammation; neuroprotection; oxidative stress.

Publication types

  • Review

Grants and funding

This research received no external funding.