[State of confusion induced by valproic acid and reversed after administration of clonazepam]

Rev Electroencephalogr Neurophysiol Clin. 1985 Sep;15(2):179-84. doi: 10.1016/s0370-4475(85)80023-x.
[Article in French]

Abstract

A 20 year old woman with complex partial seizures from childhood developed a stuporous state when her anticonvulsant therapy was substituted by VPA. She recovered when treated orally with clonazepam. This case was compared with others in the literature for which the origin of the stuporous state have been hypothesized.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Adult
  • Benzodiazepinones / therapeutic use*
  • Clonazepam / administration & dosage
  • Clonazepam / therapeutic use*
  • Cognition Disorders / chemically induced*
  • Confusion / chemically induced*
  • Drug Therapy, Combination
  • Electroencephalography
  • Epilepsy, Temporal Lobe / drug therapy*
  • Female
  • Humans
  • Valproic Acid / administration & dosage
  • Valproic Acid / adverse effects*
  • Valproic Acid / antagonists & inhibitors

Substances

  • Benzodiazepinones
  • Clonazepam
  • Valproic Acid