Native Hawaiian and Pacific Islander populations in genomic research

Edra K Ha; Daniel Shriner; Shawneequa L Callier; Lorinda Riley; Adebowale A Adeyemo; Charles N Rotimi; Amy R Bentley

doi:10.1038/s41525-024-00428-6

Native Hawaiian and Pacific Islander populations in genomic research

NPJ Genom Med. 2024 Sep 30;9(1):45. doi: 10.1038/s41525-024-00428-6.

Authors

Edra K Ha^{1

2

3}, Daniel Shriner¹, Shawneequa L Callier^{1

4}, Lorinda Riley², Adebowale A Adeyemo¹, Charles N Rotimi¹, Amy R Bentley⁵

Affiliations

¹ Center for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA.
² University of Hawai'i at Mānoa, Honolulu, HI, USA.
³ University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
⁴ Department of Clinical Research and Leadership, The George Washington University School of Medicine and Health Sciences, Washington, DC, USA.
⁵ Center for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA. amy.bentley@nih.gov.

Abstract

The role of genomic research and medicine in improving health continues to grow significantly, highlighting the need for increased equitable inclusion of diverse populations in genomics. Native Hawaiian and Pacific Islander (NHPI) communities are often missing from these efforts to ensure that the benefits of genomics are accessible to all individuals. In this article, we analyze the qualities of NHPI populations relevant to their inclusion in genomic research and investigate their current representation using data from the genome-wide association studies (GWAS) catalog. A discussion of the barriers NHPI experience regarding participating in research and recommendations to improve NHPI representation in genomic research are also included.

Publication types

Review

Abstract

Publication types

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