An open-access lumbosacral spine MRI dataset with enhanced spinal nerve root structure resolution

Sci Data. 2024 Oct 15;11(1):1131. doi: 10.1038/s41597-024-03919-4.

Abstract

Spinal cord injury (SCI) profoundly affects an individual's ability to move. Fortunately, recent advancements in neuromodulation, particularly the spatio-temporal epidural electrical stimulation (EES) targeting the spinal nerve roots, promoted rapid rehabilitation of SCI patients. Such neuromodulation techniques require precise anatomical modelling of spinal cord. However, the lack of spine imaging datasets, especially high-quality magnetic resonance imaging (MRI) datasets highlighting nerve roots, hinders the translation of EES into medical practice. To address this problem, we introduce an open-access lumbosacral spine MRI dataset acquired in 14 healthy adults, using constructive interference in steady state (CISS) sequence, double echo steady state (DESS) sequence, and T2-weight turbo spin echo (T2-TSE) sequence, with enhanced nerve root resolution. The dataset also includes the corresponding anatomical annotations of nerve roots and the final reconstructed 3D spinal cord models. The quality of our dataset is assessed using image quality metrics implemented in MRI quality control tool (MRIQC). Our dataset provides a valuable platform to promote a wide range of spinal cord neuromodulation research and collaboration among neurorehabilitation engineers.

Publication types

  • Dataset

MeSH terms

  • Adult
  • Humans
  • Lumbosacral Region / diagnostic imaging
  • Magnetic Resonance Imaging*
  • Spinal Cord Injuries / diagnostic imaging
  • Spinal Nerve Roots* / diagnostic imaging